SAFIR IMPACT BTC: precision medicine in biliary tract cancer

Participants: International coordinator -  Julien Edeline.  Team members - David Malka, John Bridgewater, Ivan Borbath, Timon Vandamme, Marjolein Homs, Angela Lamarca, Lorenza Rimassa, Anna Saborowski, Arndt Vogel, Mia Johansson, Grainne O'Kane. Patients' advocates Helen Morement (AMMF), Lilian Lecorgne (Espoir voies biliaires), Elisabeth Baucels (ATUVIBI), Paolo Leonardi (APIC), Lili Anna Kuschnereit (DiCE)

Funding agency: ATTRACT (Accelerate Together Rare Cancer Treatment) consortium; ARC, anticancer fund, fundacion cientifica contra el cancer, Kom op tegen Kanker, KWF and Rising Tide

Reference: SAFIR IMPACT BTC

Period: end 2026-end 2030

Amount: 5,100,000 €

Novel Cancer Therapy: Inducing Double-strand DNA Breaks to Foster Tumour Cell Death, Antigenicity and Immunotherapy Response in New Personalized Models (TITAN)

Participants: Coordinator - Jesus M. Banales; CoPIs - Fernando Cossio, Michela Polidoro, Jean-Charles Nault, Elena Palma

Funding agency: European Union’s Horizon 2020

Reference TRANSCAN-3 Joint Call (JTC) 2024

Peridod: end 2026-end 2028

Amount: 1,197,300 €

Patient-derived models for the Research and Evaluation of Discovery and Innovation in Combination Therapies for Biliary tract Cancer (PREDICT-BC)

Participants: Coordinator - Anna Saborowski. CoPIs - Arndt Vogel, Oreste Segatto, Gregory Schwartz, Mariano Ponz, Tian Tian

Funding agency: European Union’s Horizon 2020

Reference TRANSCAN-3 Joint Call (JTC) 2024

Peridod: end 2026-end 2028

Amount: 1,304,000 €

Toward next-generation chimeric antigen receptor therapy for cholangiocarcinoma

Participants: Coordinator - Tian Tian. Team members - Angela Lamarca, Mariano Ponz, Alena Gros, Víctor Moreno García
Funding agency: Fundación AstraZeneca

Call: 8th Young Investigator Awards, 2024 Category: Oncology, Precision Medicine and Immuno-oncology

Amount: 225,000 €

BileVision: Detection and Treatment of Bile Cancer through Liquid Biopsy and Discovery of New Therapeutic Targets

Participants: Co-PIs - Marcin Krawczyk, Matias A Avila and Carmen Berasain. Team members - Maria Arechederra, Maite G Fernandez-Barrena
Funding agency: Dr. Rolf M. Schwiete Stiftung, Mannheim, Germany
Reference: 2024-040

Amount: 250,000 €