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A guide for establishing patient-derived organoids from bile samples obtained during endoscopic procedures and performing gene expression knockdown

Rojo C, Vila JJ, Guembe L, Arrubla-Gamboa A, Jusué-Irurita V, Carrascosa-Gil J, Rullan M, Rández-Garbayo J, Fernández-Barrena MG, Huch M, Urman J, Ávila MA, Berasain C, Arechederra M
Front Cell Dev Biol. 2026 May 29;14:1812445. doi: 10.3389/fcell.2026.1812445
2026 
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Transcriptomic profiling of epigenetic regulators and metabolic reprogramming in human cholangiocarcinoma

Lopez-Pascual A, Elurbide J, Valbuena-Goiricelaya E, Latasa MU, Anaya E, Adan-Villaescusa E, Castelló-Uribe B, Martínez-Pérez LA, Uriarte I, Arechederra M, Ciordia S, Corrales FJ, Strnad P, Frankova S, Sticova E, Fabian O, Colyn L, Inacio P, Bayo J, Huch M, Berasain C, Fernández-Barrena MG, Avila MA.
Front Cell Dev Biol. 2026 Jun 4;14:1765945. doi: 10.3389/fcell.2026.1765945
2026 
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Circulating tumor DNA in biliary tract cancers: challenges, opportunities, and clinical readiness

Cadacio F, Turpin A, Rodrigues PM, Castet F, Lamarca A, Bridgewater J, Bañales JM, Macarulla T, Tian TV
Trends Cancer. 2026 May 30:S2405-8033(26)00105-6. doi: 10.1016/j.trecan.2026.05.002
2026 
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Parenteral Berberine vs Cisplatin- Loaded Lipid Nanoparticles - Development, Characterisation, Comparative Safety Profiling and Cytotoxicity in Cholangiocarcinoma Cell Models

Manov M, Stefanova D, Tzankova V, Tzankov B, Lozano E, Delgado-Calvo K, Macias RIR, Marin JJG, Spassova I, Kovacheva D, Slavkova M
Nanotechnol Sci Appl. 2026 May 20;19:596038. doi: 10.2147/NSA.S596038
2026 
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Baseline neutrophil-to-eosinophil ratio and neutrophil-to-lymphocyte ratio as prognostic markers in patients with unresectable biliary tract cancer treated with gemcitabine-cisplatin-durvalumab: an international, multicentre, retrospective cohort study

Vandeputte H, Casadei-Gardini A, Peeters F, Rimini M, Nichetti F, Saborowski A, Antonuzzo L, Passeri L, Satake T, Vivaldi C, Pressiani T, Lucchetti J, Kim JW, Abidoye O, Corallo S, Rapposelli IG, Tamberi S, Finkelmeier F, Giordano G, Pircher C, Chon HJ, Braconi C, Qaisar A, Pirrone C, Castet F, Tamburini E, Yoo C, Parisi A, Lancianese A, Diana A, Scartozzi M, Prager GW, Avallone A, Schirripa M, Kim IH, Perkhofer L, Oneda E, Verrico M, Couto N, Adeva J, Chan SL, Spinelli GP, Personeni N, Garajova I, Rodriquenz MG, Leo S, Alvim CM, Roque R, Farinea G, De Rosa A, Lanzetta I, Balsano R, Lavacchi D, Camera S, Ikeda M, Niger M, Tesini G, Tonini G, Kang M, Bekaii-Saab T, Esposito L, Boccaccino A, Ferrara M, Lo Prinzi F, Himmelsbach V, Landriscina M, Djaballah SA, Persano M, Salani F, Vogel A, Lonardi S, Fornaro L, Rimassa L, Dekervel J.
ESMO Gastrointest Oncol. 2026 May 8;12:100335. doi: 10.1016/j.esmogo.2026.100335
2026 
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